life's work

noun

: the entire or main work of a person's life
She made photography her life's work.

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Rarely has an actor's eyes been put to such good use, as Murphy's thousand-yard stare communicates guilt, regret, and anxious anticipation of how his life's work will impact the world for generations to come. — EW.com, 2 Mar. 2025 This provided her with income, but her true life's work drew on af Klint's interest in spiritualism and mysticism. — Ars Technica, 11 Jan. 2025

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“Life's work.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/life%27s%20work. Accessed 22 Mar. 2025.

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